Genome Guardian 2

Genome Guardian 2

Alpherior · March 5, 2026 · Gun Customization, Bullet Heaven, Roguelite, Action, Casual

Buy Genome Guardian 2 from Steam at $15.99 — the cheapest of 1 store we compare.

PC
Very Positive96% · 42611playing now
Best price
$15.99
lowest tracked $11.19
Steam Buy at Steam

Prices last checked

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Where to buy Genome Guardian 2 — official stores

Steam
Steam
Standard Edition · Steam
$15.99
Buy

Genome Guardian 2 price by region

Genome Guardian 2 costs £13.49 in the United Kingdom, €15.79 in Europe (EUR), $15.99 in the United States, $15.99 in Georgia (USD), CA$19.99 in Canada, A$21.99 in Australia, NZ$22.99 in New Zealand, R$47.99 in Brazil and zł66.99 in Poland right now.

Cheapest Genome Guardian 2 offer in each region, in local currency
RegionBest priceOfficial storeKey shopStores
United Kingdom £13.49 £13.49 — 1
Europe (EUR) €15.79 €15.79 — 1
United Statesyour region $15.99 $15.99 — 1
Georgia (USD) $15.99 $15.99 — 1
Canada CA$19.99 CA$19.99 — 1
Australia A$21.99 A$21.99 — 1
New Zealand NZ$22.99 NZ$22.99 — 1
Brazil R$47.99 R$47.99 — 1
Poland zł66.99 zł66.99 — 1

Each row is a real price from that region's own stores, not a currency conversion, so the figures are not directly comparable. Switch regions in the header to shop the one you buy in.

Screenshots

About Genome Guardian 2

Dive back into the microscopic world, radiating with bioluminescent life and unspeakable horrors.

Research permanent upgrades to survive a variety of microbes & modes in this massively expanded follow-up to Genome Guardian.

Build your own biomechanical death machine from different parts to define how it shoots, behaves & moves!

Make stationary turrets, psychic water sprinkler motorbikes, or maybe a dual-wielding fidget spinner Gundam.
  • Easily recreate your favourite turrets from the first game…or combine em' all into one frankenstein monstrosity
  • Save/Load 24 loadouts
  • Paint & Pattern customization

Pair DNA nucleotides A (rapidfire), C (precision), G (spread), T (explosive) to discover 70 hybrid bioweapons!

  • Shotgun + Bomb mix explosives with spread for Blast Shotgun!
  • SMG + Pistol make an accurate, fast-firing Scout Rifle!
  • Blast Shotgun + Scout Rifle = something a whole lot crazier!
  • 20-minute runs you can save & resume at any time + improved Endless Mode
  • Complete side objectives during runs for extra cash
  • Mine mineral deposits for resources
  • Trigger powerful Gadget active abilities
  • Test discovered weapons in the Database
  • 100 bassy electronic tunes with in-game Jukebox accessible any time + Streamer Mode
  • Auto aim/fire toggles
  • Localization in 10 languages
  • Full rebinding for keyboard & gamepad
  • 400% better performance/framerate on high & low-end PCs
  • Accessibility for colourblindness, motion sickness & arachnophobia
  • 100 Steam achievements
  • Cloud Save
  • Plays great on Steam Deck!

Genome Guardian 2 — game info

Platforms
Windows
Steam Deck
Playable
Player modes
Single-player
Controller
Full controller support
PC Game Pass
Not included

What Steam players say

Recent verbatim reviews from Steam — separate from playze.io community reviews below.

Recommended Sep 7, 2026
alpherior. You little ♥♥♥♥♥♥. You made a ♥♥♥♥ of piece with your trash gnome garden. It’s ♥♥♥♥♥♥♥ bad this trash game. I will become back my money. I hope you will in your next time a cow; on a trash farm, you sucker. jokes aside fun game!
2 found this helpful
Not recommended Sep 11, 2026
I have had a lot of fun with this game so far. I don't have a problem with the dev giving tips on how to build your run like a lot of the other negative reviews, you can just ignore them if you don't need them. The build diversity is good, and it is the type of game that really encourages exploring every achievement and build option, which I love. On top of that, the core gameplay is very enjoyable and keeps you coming back for more. The minor problems: - Some of the build options are literally just bad. Genuinely unusably awful. There are one or two of these options in each of the many stages you have the option to change something about your run. I get that not everything can be the same strength, and some things will only have niche use cases, but this is a bit excessive. - Stat calculations are often unclear, as well as how effects will interract with each other. Some stats will change based on your nanobot's base stats, some will go off of your weapon, some will go off your current stats, and it is unclear what will do what. I also often find myself resetting a run because I put a certain combination of gadgets, parts and mods in a build that literally just don't do anything…
1 found this helpful
Recommended Sep 10, 2026
You like classic flash games? This is the one for you. It's evolved, expanded, a bigger portion of what you've been missing. This game can have a bit of... Attitude at its player, but only with good intentions. It's solid, it's fun. The Daily Challenges force me to realize build concepts I never would have dreamed of. Loads of fun, can't wait for the next update.
1 found this helpful
Recommended Sep 10, 2026
The first game feels basic compared to this. First off, Music is a banger. Visuals are great and fun. It remembers me on an old game on windows (95, MS Dos?) that was just about shooting fireworks on your screen and watching the cool colour effects. Theres a ton of combo potential here you can experiment with. Several modes too. What is a bit annoying are the dev warnings about you doing "dumb" stuff, which is sometimes cool but also sometimes too invasive on your choices. 2 examples on that. I had a modification choice in the shop that was for a weapon i did not have. I could "Bleach" it, which would make it colourless so i could still apply it, i didnt yet though. I had to unlock a slot for that mod first, so i clicked to unlock it. The game then warned me that i didnt have anything to move into it and that this was dumb and a waste of my currency. But that didnt matter, because the game didnt know i would bleach the mod in the shop. So the dev thought it was ok to pop up 4 messages that BLOCKED me from unlocking the mod slot outright saying "Stop, what you do is dumb." Like, calm it a bit dude. Another example is that its sometimes more important to progress psychologically…
1 found this helpful
Recommended Sep 6, 2026
Game's very fun to play. I get the point of some negative reviews here. The dev gives some guidanace on what may work well or prevents you from making dumb mistakes sometimes (unlocking a "slot" without having anything to go into it right now). If they are reading this, add an option to toggle that sort of thing on/off and display that at the start. Requires writing some alternative text for weapons etc in the game but it'd certainly help the people familiar with the genre/adress these complaints.
1 found this helpful
Recommended Sep 4, 2026
I don't like the tutorial forcing me to do things, let me play the game at my own pace, I'll discover it when I get there
1 found this helpful

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