S.E.M.I. – Side Effects May Include...

S.E.M.I. – Side Effects May Include...

Two Horn Unicorn · January 23, 2026 · Co-op, Platformer, Physics, Multiplayer, Online Co-Op

Buy the S.E.M.I. – Side Effects May Include... key for Steam from Kinguin at $1.59 — the cheapest of 2 stores we compare.

PC
Very Positive86% · 113
Best price 75 Lowest tracked
$1.59-80%
⭐ lowest tracked
Kinguin Buy at Kinguin

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Where to buy S.E.M.I. – Side Effects May Include... — official stores

Steam
Steam
Standard Edition · Steam
$7.99
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Cheapest S.E.M.I. – Side Effects May Include... keys — keyshops

Keyshops are third-party marketplaces — keys are resold and can be region-locked or a different edition. Check the listing's region & edition before buying.

Kinguin
Standard Edition · Steam
$1.59
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S.E.M.I. – Side Effects May Include... price by region

S.E.M.I. – Side Effects May Include... costs £1.04 in the United Kingdom, €1.20 in Europe (EUR), $1.59 in the United States, $1.59 in Georgia (USD), zł6.70 in Poland, CA$10.49 in Canada, A$11.79 in Australia, NZ$11.79 in New Zealand and R$19.99 in Brazil right now.

Cheapest S.E.M.I. – Side Effects May Include... offer in each region, in local currency
RegionBest priceOfficial storeKey shopStores
United Kingdom £1.04 −84% £6.69 £1.04 2
Europe (EUR) €1.20 −85% €7.79 €1.20 2
United Statesyour region $1.59 −80% $7.99 $1.59 2
Georgia (USD) $1.59 −47% $2.99 $1.59 2
Poland zł6.70 −73% zł24.99 zł6.70 2
Canada CA$10.49 CA$10.49 — 1
Australia A$11.79 A$11.79 — 1
New Zealand NZ$11.79 NZ$11.79 — 1
Brazil R$19.99 R$19.99 — 1

Each row is a real price from that region's own stores, not a currency conversion, so the figures are not directly comparable. Switch regions in the header to shop the one you buy in.

Screenshots

About S.E.M.I. – Side Effects May Include...

✦ AI summary

S.E.M.I. – Side Effects May Include... is a chaotic cooperative escape game where you and up to three friends fight through a mental clinic filled with puzzles, combat, and brutal platforming while wielding randomized pill-based abilities that range from helpful to hilariously uncontrollable. Wildly unpredictable power-ups, dynamically generated rooms with shifting gravity and deadly traps, and the constant threat of your own team becoming your worst enemy make every escape attempt a frantic test of communication and improvisation.

S.E.M.I. is a single-player and co-op action platformer with puzzle elements. Play as patients of an unusual clinic, take experimental drugs, interfere with each other, and be ready for chaos and unpredictable side effects!

S.E.M.I. – Side Effects May Include... — game info

Platforms
Windows
Player modes
Single-player, Online co-op
Controller
Full controller support
PC Game Pass
Not included

DLC & expansions

🎁 Complete the collection

Base game + 1 of 1 DLC at today's best prices.

$3.58
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What Steam players say

Recent verbatim reviews from Steam — separate from playze.io community reviews below.

Recommended Jul 17, 2026
определённо да, игра весит всего гигабайт но играется с полным угаром из миинусов оптимизация игра хоть и весит мало но извините, фпсов не хватает а так в целом охуительно
Recommended May 14, 2026
So fun game to play with friends. U actually have to use brain. The only real issue I had was motion blur. If you have it turned off, it still feels on at times, which can grate during fast motion. I just hope the devs take it out completely in an update. Overall, a very fun co-op game 8/10
Recommended Apr 25, 2026
I honestly love how goofy this game is. It is so much fun! I love the different 'side effects' and the customisation of the characters. The puzzles are funny too, I don't find them stressful. All in all I find this is a nice chill game!
Recommended Mar 31, 2026
[h1]Weird but Fun Platformer![/h1] This one was definitely fun with friends. We did have someone who wasn't the best at platformers, but think we all enjoyed it! The Puzzles were challenging and the effects from the "medicines" had some interesting effects. I'd recommend if you want a game to play with a group of friends!
Recommended Mar 22, 2026
This game is pure chaos. Its a lot of fun with close friends. The pill side effects are hysterical and the puzzles are interesting enough that you can get stuck. The way you are downed is so stupid and funny we spent to much time just hurting each other. 10/10 game experience.
Recommended Mar 13, 2026
Played this with my wife and we had a surprisingly good time. It can be a bit difficult at first, but that actually makes it more satisfying once you get the hang of it. The overall theme of the game is completely crazy (sorry… couldn’t resist the pun 😅), and the unpredictable abilities and side effects make every run feel chaotic in a fun way. I really like the customization options and the general design of the game. The art style and characters are pretty cool, and unlocking new outfits and decorations adds a nice extra layer to the experience. The idea behind the game is also quite original. Running through rooms, dealing with traps, fighting enemies, and dealing with random pill side effects keeps things unpredictable and entertaining the whole time. The levels and challenges keep you busy and engaged, especially when playing together. Overall, a fun and weird co-op experience that’s great to play with friends or your partner.

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